Clinical Research

The Foundation for Retinal Research

We conduct Clinical Research Studies through our Foundation for Retinal Research, offering our patients and physicians access to cutting edge treatments and procedures in a variety of ophthalmic conditions and diseases. We’ve participated in numerous studies involving Macular Degeneration, Diabetic Retinopathy, and Retinal Vein Occlusion, among others, and we are continuously seeking new Clinical Research Studies to better serve our patients and partners.

Our Foundation for Retinal Research currently has four ongoing studies:

1. Novartis – CLNP023E12201 A multicenter, randomized, participant and investigator masked, placebo controlled, proof-of-concept study to assess the safety and efficacy of Iptacopan (LNP023, a complement Factor B inhibitor) in participants with early to intermediate age-related macular degeneration in one eye and neovascular age-related macular degeneration in the other eye. Novartis Website   Clinicaltrials.gov 
2. OcuTerra Therapeutics Diabetic Retinopathy Study – OTT166-201 A Phase 2 Randomized, Multicenter Study to Evaluate the Safety and Efficacy of OTT166 (an Integrin Inhibitor) Ophthalmic Solution  in the Treatment of Diabetic Retinopathy (DR). For more information:  OcuTerra Website  Clinicaltrials.gov   Literature Review  
3. Character Biosciences AMD Progression Study – A Long Term Observational Study into the Progression of Non-Exudative Age-Related Acute Macular Degeneration (Dry AMD). Character Biosciences
4. Apellis APL2-GA-305 – A Phase 3, Open Label, Multicenter Extension Study to Evaluate the Long Term Safety and Efficacy of Pegcetocoplan in Patients with Geographic Atrophy Secondary to Age-Related Macular Degeneration.  Clinical Trials.gov   Literature  

Recently Completed Studies:

1. Apellis APL2-304 – A Phase 3, Multi-Center, Randomized Double-Masked, Sham-Controlled Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy with SHAM Injections in Patients with Geographic Atrophy Secondary to Age Related Macular Degeneration
2. Regeneron Pharmaceuticals VEGFe-HD-DME-1934 –  A Randomized, Double Masked Active Controlled Phase 2/3 Study of the Efficacy and Safety of High Dose Aflibercept in Patients with Diabetic Macular Edema (PHOTON)
3. Neurotech Pharmaceuticals NTMT-03-A – A Phase 3, Multicenter, Randomized, Sham-Controlled Study to Determine the Safety and Efficacy of Renexus in Macular Telangiectasia Type 2

If you are interested in participating in clinical research trials or referring patients for participation in our studies, please contact Amanda Byers or Brent Fodera at (504) 265-1818.

Physicians, please click here to find out more about our research and fellowship opportunities.